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[Remote] Staff Machine Learning Engineer, AI Generation Engine

Work from home Full-time role Hiring

Note: The job is a remote job and is open to candidates in USA. SandboxAQ is a high-growth company delivering AI solutions that address some of the world's greatest challenges. The AI Generation Engine (SAIGE) team is seeking a highly accomplished Machine Learning Engineer to take ownership of the end-to-end ML lifecycle, focusing on designing and building AI-first products that leverage Large Quantitative Models (LQMs).

Responsibilities

  • Design, construct, and manage robust data pipelines for the training, validation, and continuous retraining of Large Quantitative Models (LQMs) and agentic frameworks
  • Develop, implement, and rigorously test novel ML models and algorithms, defining appropriate metrics to ensure model performance aligns with high-level product objectives
  • Lead the effort in cleaning, transforming, and engineering features from complex and large-scale datasets to optimize LQM performance and predictive accuracy
  • Conduct deep analysis of model behavior, performance, and failure modes, tuning hyper-parameters and optimizing model architecture for efficiency, speed, and accuracy in a production context
  • Collaborate closely with AI researchers, product managers, and SWEs to translate high-level business objectives into actionable ML development and deployment roadmaps
  • Champion and enforce exceptional engineering standards for code quality, system efficiency, and security in a prototyping environment
  • Drive technical execution with high autonomy, making critical design and implementation decisions independently

Skills

  • BS in Software Engineering, Computer Science, or equivalent field of study
  • 8+ years of postgraduate experience in software development
  • Experience developing highly-available, performant, scalable ML systems, including large-scale data processing pipelines
  • Strong expertise in Python (including the ML stack: PyTorch, TensorFlow, JAX, NumPy, Pandas)
  • Long, successful history of driving the full ML lifecycle: from initial data exploration and hypothesis testing to architecture, model training, evaluation, and production deployment
  • Deep proficiency in MLOps and software best practices, including CI/CD for ML, experiment tracking (e.g., Weights & Biases, MLflow), automated testing, and version control for both code and datasets
  • MS or PhD in Software Engineering, Computer Science or equivalent experience
  • Financial simulation or technical experience, risk simulation
  • Equivalent experience includes tech leadership in a complex space, driving technical design and execution cross-collaboratively across multiple teams and organizations
  • Experience with scalable software development on cloud computing platforms (e.g., GCP, AWS)

Benefits

  • Comprehensive medical, dental, and vision coverage for employees and dependents with generous employer premium contributions
  • Retirement savings with company matching
  • Paid parental leave
  • Inclusive family-building benefits
  • Flexible paid time off
  • Company-wide seasonal breaks
  • Support for flexible work arrangements that enable sustainable performance
  • Opportunities for continuous learning and growth through on-the-job development, cross-functional collaboration, and access to internal learning and development programs

Company Overview

  • SandboxAQ develops AI and quantum technology solutions that enhance biopharma, cybersecurity, and materials science. It was founded in 2016, and is headquartered in Palo Alto, California, USA, with a workforce of 51-200 employees. Its website is https://www.sandboxaq.com.
  • Company H1B Sponsorship

  • SandboxAQ has a track record of offering H1B sponsorships, with 7 in 2025, 6 in 2024, 3 in 2023, 5 in 2022, 1 in 2021, 5 in 2020. Please note that this does not guarantee sponsorship for this specific role.
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