Principal Software Architect

Title21 Health Solutions is a leading provider of innovative healthcare IT solutions, dedicated to improving patient care and streamlining operations for healthcare organizations worldwide. We are seeking an experienced Principal Software Architect to define and lead enterprise-wide technical architecture, drive platform innovation, and ensure our solutions are scalable, secure, and compliant in highly regulated healthcare environments. Job Responsibilities: Own and evolve the end-to-end technical architecture of the Unexa platform — spanning data persistence, service boundaries, API contracts, integration patterns, and frontend delivery. Lead the definition and governance of architectural standards across cloud, data, application, and infrastructure domains, ensuring business objectives are reflected in every technical decision. Champion SOA, microservices, and event-driven paradigms, architecting message broker and async event pipeline strategies that decouple services, maximize resilience, and enable audit-grade traceability at scale. Drive BPMN-compliant workflow modeling as a platform-wide engineering discipline, ensuring process orchestration is explicit, auditable, and maintainable across regulated workflows. Establish and own data architecture standards across PostgreSQL and MS SQL Server environments, with authoritative command over schema design, normalization strategies, indexing, query optimization, and migration governance at enterprise scale. Architect comprehensive data ecosystems spanning master data management (MDM), analytics platforms, OpenSearch, Redis caching, and data lake patterns that serve both operational and regulatory needs. Define data partitioning, archival, and retention strategies that satisfy FDA regulatory expectations while meeting performance SLAs. Govern ORM usage, stored procedure policies, and data access layer abstractions, and lead the evolution of our data architecture in response to scale, compliance, and product changes. Define and enforce security principles across the full stack as first-class architectural concerns — including authentication and authorization models (OAuth 2.0, OIDC, RBAC, ABAC), secrets management, encryption at rest and in transit, and API gateway security policies. Lead threat modeling exercises, architect penetration test remediation strategies, and ensure the platform meets GDPR, HIPAA, SOC 2 Type 2, ISO 27001, and FDA 21 CFR Part 11 at every layer. PII/PHI handling and audit logging are embedded in every architectural pattern, not added as afterthoughts. Drive Computer System Validation (CSV) and Computer System Assurance (CSA) alignment across our regulated system portfolio. Establish and govern REST and GraphQL API design standards that treat internal and external API contracts as first-class products — versioned, reusable, and purpose-built for multi-surface consumption across web, mobile, and third-party integrations. Lead the architecture and continuous evolution of our API gateway layer, including rate limiting, authentication enforcement, observability hooks, and developer experience tooling. Define integration architecture patterns that support both synchronous and event-driven communication across the platform. Define the platform’s strategic approach to AI and ML integration, establishing architectural patterns for responsible, auditable AI usage in regulated environments. Lead the evaluation and adoption of AI-assisted quality workflows within Unexa 2.0, ensuring AI-driven features meet the same compliance and auditability standards as the rest of the system. Guide the engineering organization in identifying and integrating emerging technologies that provide strategic advantage while maintaining operational integrity. Function as the primary technical mentor and organizational role model for the entire engineering organization. Conduct architecture reviews, establish coding and design standards, and lead design sessions that measurably build engineering capability across all levels. Produce comprehensive architectural documentation, including Architecture Decision Records (ADRs), system diagrams, data flow documentation, and domain-specific standards that serve as the authoritative reference for engineering decisions. Lead the internal technical community of practice, fostering a culture of architectural discipline and engineering excellence. Collaborate with the CTO and Product leadership to translate multi-year business roadmaps into architectural strategies, ensuring developers understand not just what to build but why. Qualifications: 8-10+ years of progressive software engineering experience, with at least 7 years in a formal senior architecture or principal engineer role Demonstrated ownership of platform-wide architectural vision across multi-team, multi-year, multi-million-dollar initiatives Deep expertise in Python backend development and TypeScript/JavaScript frontend frameworks, with a track record of leading teams that ship production-grade systems at scale Expert-level database architecture experience across PostgreSQL and MS SQL Server — including performance tuning, schema governance, migration management, and data modeling for regulated environments Authoritative command of API design principles — REST, GraphQL, versioning strategies — with a proven track record of building and governing API-first platforms Deep hands-on experience with event-driven architecture using Kafka, RabbitMQ, AWS EventBridge, or equivalent Expert-level experience with BPMN-based workflow modeling and orchestration (Camunda, Flowable, or similar), including regulated use cases Mastery of cloud-native architectures and cloud-agnostic design patterns, with direct experience driving cloud platform strategy Experience with OpenSearch, Redis, MDM, analytics platforms, and data lake architectures Demonstrated expertise designing and governing security architecture in regulated or compliance-driven environments at enterprise scale Proven experience integrating AI/ML platforms, data pipelines, and modern engineering practices into regulated production systems Exceptional communication skills — able to architect narratives for executive audiences, engineers, and regulators alike Track record of developing senior engineers and architects into autonomous technical leaders Position Type: Remote (Eastern Time Zone, United States) Full-Time Employment; Exempt Travel: Up to 15% Physical Requirements: This position primarily operates in a professional office environment. While performing the duties of this job, the employee is regularly required to sit. The employee is occasionally required to stand, walk, reach with hands and arms, and lift up to 20 pounds. Apply To This Job